Promotionsvortrag Physik: Detection of single Molecules with plasmonic enhancened Microcavities

Dez 08
8. Dezember 2017 13:30 Uhr bis 15:00 Uhr
Seminarraum 1.500, Max – Planck- Institut für die Physik des Lichtes, Staudtstraße 2, Erlangen

Einladung zum Promotionsvortrag von Herrn Martin Baaske:
„Detection of single Molecules with plasmonic enhancened Microcavities“

Optical whispering gallery mode (WGM) microresonators, by virtue of their high quality factors and small mode volumes, have developed into versatile tools for bio-sensing and especially for the recognition of small entities such as nanoparticles and viruses.
By utilizing resonant coupling between WGMs in fused silica microspheres and the localized surface plasmons supported by gold nanoparticles this detection capability can be further boosted to a level at which single molecules, their interactions and conformational changes can be resolved.
Following on a brief introduction of the overall sensor assembly and function, I will discuss the observation of various intermolecular and molecule-surface interactions with focus on the sequence specific transient and permanent DNA-hybridization reactions between short oligonucleotides.
Furthermore I will show WGM-sensor data obtained by monitoring the interactions between gold nanorods and single Zinc(II) and Mercury(II)-ions and their dependence on the overall ionic strength of the surrounding aqueous medium. (Vortrag auf Englisch)

Dem Vortrag schließt sich eine Diskussion von 15 Minuten an. Vortrag und Diskussion sind öffentlich. Diesen Verfahrensteilen folgt ein nicht öffentliches Rigorosum von 45 Minuten.